Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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Inhibitory Effect of a Chinese Quince Seed Peptide on Protein Glycation: A Mechanism Study
Yejun Deng, Xiang Wang, Caihong Zhang, Pujun Xie, Lixin Huang
 doi: 10.1016/j.jobab.2023.01.008
[Abstract](0) [PDF 1094KB](0)
Non-enzymatic glycation can cause the formation and accumulation of advanced glycation end products (AGEs), and it poses great threats to human health. It is urgent to search for safe and efficient inhibitors to prevent reducing sugar induced protein glycation. In this study, we investigated the anti-glycation activity and mechanism of an identified peptide, Asparagine-Tyrosine-Arginine-Arginine-Glutamic acid (NYRRE) from Chinese quince seed protein hydrolysate, by multispectroscopy, confocal imaging, and computational molecular simulation. Firstly, it was found that NYRRE could scavenge hydroxyl radicals and chelate Fe2+. Besides, the NYRRE was effective in every stage of fructose induced bovine serum albumin (BSA) glycation. The NYRRE could reduce the formation of fructosamine, carbonyl compounds, glycoxidation products and β-amyloid structure. Meanwhile, NYRRE could protect thiol groups and stabilize the spatial conformation of BSA. The NYRRE presented strong inhibition in fluorescent AGEs, and 68.19% of total AGEs formation was prevented with NYRRE at 15 mmol/L. The results of molecular simulation indicated that NYRRE could insert into the hydrophobic pocket of BSA and interact with hot spots, including arginine and lysine residues. The mechanism of NYRRE inhibiting protein glycation could be due to its antioxidant activity, BSA structure stabilizing ability, and specific bond with glycation sites of BSA. These results provided a valuable reference for developing NYRRE as an efficient antiglycation agent in preventing glycation-mediated diseases.
Pichia as Yeast Cell Factory for Production of Industrially Important Bio-Products: Current Trends, Challenges, and Future Prospects
Akansha Shrivastava, Mamta Pal, Rakesh Kumar Sharma
 doi: 10.1016/j.jobab.2023.01.007
[Abstract](0) [PDF 1300KB](0)
Yeast has been used as a cell factory for thousands of years to produce a wide variety of complex biofuels, bioproducts, biochemicals, food ingredients, and pharmaceuticals. For a variety of biotechnological production hosts, a few specific genera of yeast have proven themselves. Rapid developments in metabolic engineering and synthetic biology provide a workable long-term supply solution for these substances. In this review, we have covered recent advances in the design of yeast cell factories for the synthesis of terpenoids, alkaloids, phenylpropanoids, and other natural chemicals, primarily focusing on Pichia species. Cutting-edge solutions involving genetic and process engineering have also been discussed. Overall, the review summarized recent advancements and challenges in synthetic and systems biology, as well as initiatives in metabolic engineering aimed at commercializing non-conventional yeasts like Pichia. The processes used in non-traditional yeasts to produce enzymes, therapeutic proteins, lipids, and metabolic products for industrial applications were thoroughly elaborated.
Antimicrobial and Antibiofilm Activities of Pomegranate Peel Phenolic Compounds: Varietal Screening Through a Multivariate Approach
Amira Salim, Pierfrancesco Deiana, Francesco Fancello, Maria Giovanna Molinu, Mario Santona, Severino Zara
 doi: 10.1016/j.jobab.2023.01.006
[Abstract](3) [PDF 1565KB](0)
Super-Anti-Freezing, Tough and Adhesive Titanium Carbide and L-Ornithine-Enhanced Hydrogels
Zhangkang Li, Jamie LeBla nc, Hitendra Kumar, Hongguang Zhang, Weijun Yang, Xiao He, Qingye Lu, Jeffrey Van Humbeck, Keekyoung Kim, Jinguang Hu
 doi: 10.1016/j.jobab.2023.01.005
[Abstract](1) [PDF 3033KB](0)
In-situ Polymerization of Lignocelluloses of Autohydrolysis Process with Acrylamide
Haosong Zhao, Weijue Gao, Pedram Fatehi
 doi: 10.1016/j.jobab.2023.01.004
[Abstract](1) [PDF 1411KB](0)
Efficient Synthesis of Alkyl Levulinates Fuel Additives Using Sulfonic Acid Functionalized Polystyrene Coated Coal Fly Ash Catalyst
Yi Tian, Xiaoting Zhu, Shuolin Zhou, Wenguang Zhao, Qiong Xu, Xianxiang Liu
 doi: 10.1016/j.jobab.2023.01.003
[Abstract](1) [PDF 1137KB](0)
Papaya Peel Waste Carbon Dots/Reduced Graphene Oxide Nanocomposite: from Photocatalytic Decomposition of Methylene Blue to Antimicrobial Activity
Hesam Salimi Shahraki, Rani Bushra, Nimra Shakeel, Anees Ahmad, Quratulen, Mehraj Ahmad, Christos Ritzoulis
 doi: 10.1016/j.jobab.2023.01.009
[Abstract](0) [PDF 3431KB](0)
Carbon dots (CDs) have gained unprecedented attention as a novel luminescent zero-dimensional carbon nanomaterial owing to their diverse industrial applications. Herein, we reported the sustainable synthesis of fluorescent CDs from papaya peel waste, acting as a natural carbon originator. As-prepared CDs and reduced graphene oxide (RGO) were fabricated in the composites through a facile one-step hydrothermal method. Synthesized RGO/CDs (RC) nanocomposites were characterized using spectroscopic, diffraction, and electron-microscopic techniques. Nanocomposites with variable RGO to CD mass ratios were tested for photodegradation of textile dye methylene blue (MB). The highest photocatalytic activity (degradation efficiency of 87% in 135 min) was obtained in the nanocomposite containing a 2꞉1 mass ratio (RC2). The RGO sheets in the nanocomposite acted as media for electron acceptors, promoting the fast transfer and separation of photoinduced electrons during CDs excitation, thus preventing the recombination of the electron and holes. Based on the agar well diffusion assay, the nanocomposites exhibited excellent antibacterial activity than other tested materials against Bacillus subtilis (Gram-positive) and Pseudomonas aeruginosa (Gram-negative) bacterium. The largest inhibition zone area (22 mm), i.e., the highest antimicrobial activity, was obtained in the nanocomposite tested against Gram-positive strains. Taken together, the synergistic effect of RGO and CDs enhanced the photocatalytic and antibacterial performance of synthesized nanocomposite material.
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Electrochemical valorization of lignin: Status, challenges, and prospects
Jian Luo, Tianbiao Leo Liu
2023, 8(1): 1-14.   doi: 10.1016/j.jobab.2022.11.003
[Abstract](2) [FullText HTML](3) [PDF 3867KB](0)
As the second most abundant component of lignocellulosic biomass and the largest source of renewable aromatic compounds, lignin shows great potential to replace finite, non-renewable fossil oils and becomes a renewable feedstock for the production of fuel and aromatic chemicals. Therefore, it is highly important to develop efficient methods to convert lignin into biofuels and valuable chemicals. Electrochemical approaches are considered to be scalable, oxidant/reductant free, easy to control, and can be conducted under mild conditions. This review firstly overviews the structure and deconstruction methods of lignin. And then, different electrochemical lignin conversion approaches, including mediated electrooxidation, electroenzymatic oxidation, photoelectrochemical oxidation, and direct electrooxidation, are discussed in detail. The application of lignin-derived monomeric compounds is also briefly introduced. Finally, the advantages and challenges of different electrochemical lignin upgrading approaches are summarized; meanwhile, suggestions are made for future research on lignin biomass valorization.
Advances and challenges of cellulose functional materials in sensors
Hongwei Ma, Zhiyong Cheng, Xiaobai Li, Bin Li, Yujie Fu, Jianchun Jiang
2023, 8(1): 15-32.   doi: 10.1016/j.jobab.2022.11.001
[Abstract](0) [FullText HTML](0) [PDF 5512KB](0)
As the most abundant natural polymer material on the earth, cellulose is a promising sustainable sensing material due to its high mechanical strength, excellent biocompatibility, good degradation, and regeneration ability. Considering the inherent advantages of cellulose and the success of modern sensors, applying cellulose to sensors has always been the subject of considerable investigation, and significant progress has been made in recent decades. Herein, we reviewed the research progress of cellulose functional materials (CFMs) in recent years. According to the different sources of cellulose, the classification and preparation methods for the design and functionalization of cellulose were summarized with the emphasis on the relationship between their structure and properties. Besides, the applications of advanced sensors based on CFMs in recent years were also discussed. Finally, the potential challenges and prospects of the development of sensor based on CFMs were outlined.
Lignocellulose pretreatment by deep eutectic solvents and related technologies: A review
Penghui Li, Chi Yang, Zhengwei Jiang, Yongcan Jin, Wenjuan Wu
2023, 8(1): 33-44.   doi: 10.1016/j.jobab.2022.11.004
[Abstract](1) [FullText HTML](1) [PDF 1952KB](0)
Lignocellulose is the main component of plants and has a wide range of sources. The high-value production of lignocellulose lies in the biorefinery of lignin, cellulose and hemicellulose. The advantages and disadvantages of traditional lignocellulose pretreatment methods were summarized, and the effective pretreatment parameters were listed. As a green solvent system with excellent performance, deep eutectic solvents (DES) are considered to be the most potential biomass pretreatment system. Based on this, the new trend and progress of DES in lignocellulose pretreatment were reviewed, focusing on the effects of distinct kinds of lignocellulose raw materials, distinct components of DES, distinct reaction conditions and assisted by microwave ultrasound on the pretreatment of lignocellulose, and the recyclability of DES solution system was discussed. Finally, the application and development direction of DES in lignocellulose pretreatment are proposed and prospected.
Research Artcile
Assessment of densified fuel quality parameters: A case study for wheat straw pellet
Bidhan Nath, Guangnan Chen, Les Bowtell, Ahmed Mahmood Raid
2023, 8(1): 45-58.   doi: 10.1016/j.jobab.2022.10.001
[Abstract](0) [FullText HTML](0) [PDF 2348KB](0)
An investigation was conducted to examine the impact of additive mixing with wheat straw (WS) for pellet making. This study manufactured seven types of pellets with different additive combinations to evaluate pellet quality characteristics and their relationships. A laboratory-type hammer mill and a pellet mill were used for feedstock preparation and pellet production. Experimental investigations showed that the lignin content increased from 7.0% to 13.1%, which was a primary need for pelletization. Also, the heating value rose from 17.02 to 20.36 MJ/kg. However, the ash content also increased from 7.09% to 16.2%. Results showed that dimension (length and diameter), durability, and tensile strength increased significantly with additives while the fines content decreased. The fines content had an inverse relationship with durability and strength. Wheat straw (60%), together with 10% sawdust (SD), 10% corn starch (CS), 10% bentonite clay (BC), and 10% biochar (BiC), was optimal with good pellet performance (T7). In addition, both the T5 pellets (70% WS, 10% SD, 10% BiC, and 10% BC) and the T6 pellets (70% WS, 10% SD, 10% BiC, and 10% CS) provide suitable quality according to EN plus 2015 standard requirements. The ash content of produced pellet was higher than the recommended value, which suggests that further research onto the alternative additive use for ash reduction is needed.
Exploitation of the antibacterial, antibiofilm and antioxidant activities of Salvadora Persica (Miswak) extract
M. El-Sherbiny Gamal, Mohamed Gazelly Ahmed, H. Sharaf Mohammed, A. Moghannemm Saad, M.E Shehata, K.A. Ismail Mahmoud, S. El-Hawary Ahmad
2023, 8(1): 59-65.   doi: 10.1016/j.jobab.2022.11.006
[Abstract](0) [FullText HTML](1) [PDF 929KB](0)
The Salvadora persica (S. persica) L. chewing stick, usually known as miswak, is still being employed as an oral hygiene agent for plaque and gingivitis prevention. This study aims to assess the antibacterial, antibiofilm, antioxidant, and phytochemical profile of S. persica extract. The S. persica was purchased from a local market, grinded and extracted with petroleum ether. The disk diffusion, microdilution, and micro-plate assays were performed to evaluate the antibacterial and antibiofilm activities of the prepared extract at different concentrations against β-lactam resistance Streptococcus species. Free radical scavenging 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and stable radical cationic chromophore, 2, 2-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) methods were used to determine their antioxidant activity. Chromatographic and spectrometric analyses were performed using gas chromatography-mass (GC-MS) spectrometry. The minimum inhibitory concentration (MIC) of S. persica extract against β-lactam resistance Streptococcus species ranged from 6.25 to 12.5 mg/mL. The maximum suppression of biofilm formation by S. persica extract was observed at MIC with a percentage of 68.66%, against Streptococcus oralis. The S. persica extract exhibited antioxidant activity with IC50 of 20 µg/mL and 35 µg/mL from DPPH and ABTS, respectively. The phytochemical characterization showed the presence of 22 compounds with major compounds; benzyl isothiocyanate (36.21%) and n-hexadecanoic acid (27.62%). The S. persica extract exhibited antibacterial activity against β-lactam resistant Streptococcus species, showing a promising natural alternative that could be a treatment option.
Adsorption Isotherm and Kinetic Study of Methane on Palm Kernel Shell-Derived Activated Carbon
Mohd Saufi Md Zaini, Muhammad Arshad, Syed Shatir A. Syed-Hassan
2023, 8(1): 66-77.   doi: 10.1016/j.jobab.2022.11.002
[Abstract](0) [FullText HTML](0) [PDF 2016KB](0)
Activated carbon (AC) was synthesized from palm kernel shell (PKS) using different activating agents, i.e., steam, carbon dioxide (CO2), and CO2-steam, in order to analyze the impact of activating agents on the pore opening of AC. In this study, AC produced from PKS was found to have great potential as an adsorbent for methane storage. The different molecular diffusivity and reactivity of the combination of CO2 and steam succeeded in producing AC with the highest burn-off of 78.57%, a surface area of 869.82 m2/g, a total pore volume of 0.47 cm3/g, and leading to maximum methane gas adsorption capacity of 4.500 mol/kg. All types of ACs exhibited the best fit with the Freundlich isotherm model, with the correlation coefficient (R2) ranging from 0.997 to 0.999, indicating the formation of multilayer adsorption. In addition, the adsorption kinetic data for all ACs followed the pseudo-first-order model showing that the rate of adsorption was dependent on both the adsorbent and the adsorbate and was governed primarily by physical adsorption between the pore surface and methane gas. The results of intraparticle diffusion model indicated that the adsorption of methane was affected by both pore diffusion and exterior layer diffusion due to the different adsorption rates.
Development and characterization of mycelium bio-composites by utilization of different agricultural residual byproducts
Liucheng Peng, Jing Yi, Xinyu Yang, Jing Xie, Chenwei Chen
2023, 8(1): 78-89.   doi: 10.1016/j.jobab.2022.11.005
[Abstract](2) [FullText HTML](0) [PDF 2227KB](0)
Mycelium bio-composites was developed by incubating Pleurotus ostreatus fungi on different substrates from agricultural residual byproducts, including rice straw, bagasse, coir-pith, sawdust, and corn straw. The scanning electron microscope (SEM) results showed that the hypha of composite derived from bagasse was the densest, and the diameter of hypha was the biggest (0.77 µm), which was presumably due to the existence of cellulose in bagasse in the form of dextran and xylan. The maximum and minimum compression strength for sawdust substrate and corn straw substrate were 456.70 and 270.31 kPa, respectively. The flexural strength for bagasse substrate and rice straw substrate were 0.54 and 0.16 MPa, respectively. The two composites derived from rice straw and bagasse exhibited higher hydrophobic properties than others. In comparison, mycelium bio-composite derived from bagasse showed the best comprehensive properties. Except for a little worse anti-creep ability and waterproof performance, other properties of mycelium bio-composites could be comparable to commercially expanded polystyrene (EPS) packaging material. Derived from this study, mycelium material provided a good way to use agricultural residual byproducts and could be a good alternative to non-biodegradable materials for packaging applications.
Erratum regarding previously published articles 
2023, 8(1): 90-92.  
[Abstract](4) [PDF 200KB](3)
Erratum regarding previously published articles 
2023, 8(1): 93-95.  
[Abstract](0) [PDF 202KB](1)
Erratum regarding previously published articles 
2023, 8(1): 96-97.  
[Abstract](1) [PDF 208KB](1)
Erratum regarding previously published articles
2023, 8(1): 98-99.  
[Abstract](0) [PDF 188KB](1)
Current Issue

Year 2023 Vol. 8 No.1

Table of Contents


ISSN 2369-9698

J. Bioresour. Bioprod.


Started in 2016

Huining Xiao, Prof.

University of New Brunswick, Canada


Jianchun Jiang, Prof.

Institute of Chemical Industry of Forest Products, Chinese Academy of Forestry, China